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What is an MIP[4]SPE?:

Molecularly Imprinted Polymers for Solid Phase Extraction (a.k.a. MIP[4]SPE), are solid phase extraction columns designed for unparalleled selectivity toward a particular target compound, or class of compounds.  MIP[4]SPE combines the selectivity of an antibody with the stability of a polymer.  The benefits provided by MIP[4]SPE compared with conventional silica-based, and mixed-bed SPE columns, include:

  • Cleaner extracts, reduced background interferences

  • Improved sensitivity

  • Consistently high target analyte recovery

  • Reduced sample preparation time

  • Fewer sample clean-up steps

  • Elimination of ion-suppression in LC/MS applications


Currently available MIP[4]SPE products:

  • beta-Agonist drugs (class specific)

  • beta-Blocker drugs (class specific)

  • beta-Receptor (beta-Agonists + beta-Blockers)

  • Chloramphenicol

  • Clenbuterol

  • NNAL (carcinogenic tobacco-specific nitrosamine)

  • Riboflavin (Vitamin B2)

  • Tobacco-specific nitrosamines (NNN, NNK, NAB, & NAT)

  • Triazine herbicides (class specific)

  • ExploraSep Method Development Kits

  • others are in development

These standard solid-phase extraction products are available in standard 10 mL column format.  Other formats including 3 mL columns, 96-well plate format, etc., are also available.  MIP sorbents can also be also be formatted to create selective HPLC columns.

 
In short, MIP delivers better results, greater productivity, and lower costs.


MIPs can also be used for process-scale clean-ups.
 

 


Your compound's not listed? ... No problem!


Find out more about:


Ask about our method development kits (ExploraSep) and our risk-free evaluation service (MIP-Screen), to see if a MIP in our extensive library will work for your application.  Where standard products do not exist, custom designed MIPs can be developed.

         

 


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